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Laryngeal Physiology Laboratory

Laryngeal Physiology Laboratory

The Laryngeal Physiology Laboratory has been active in research for over 20 years and is designed to conduct in vivo experiments in laryngeal physiology. The laboratory is a fully equipped surgical suite designed to study how the larynx controls voice production.  The goal is to expand our understanding of voice disorders in a laboratory setting and to translate the findings into clinical care of people with voice disorders.

Current Research Projects

  • Neuromuscular control of the larynx
  • Ex vivo living larynx
  • Laryngeal transplantation

Funding Source:
NIH/NIDCD R01DC011300   Neuromuscular Control of the Larynx   (PI: D. Chhetri)

Members

Recent Publications

  • Chhetri DK, Neubauer J, Berry DA. Neuromuscular control of fundamental frequency and glottal posture at phonation onset. J. Acoust. Soc. Am. 2012 Feb; 131(2):1401-1412. (PDF)
  • Chhetri DK, Neubauer J, Berry DA. Graded activation of the intrinsic laryngeal muscles for vocal fold posturing. JASA. 2010 Apr; 127(4) :EL121-EL152
  • Berke GS, Neubauer J, Berry DA, Ye M, Chhetri DK. Ex vivo perfused larynx model of phonation: preliminary study. Ann Otol Rhinol Laryngol. 2007 Nov;116(11):866-70.
  • Döllinger M, Berry DA, Berke GS. Medial surface dynamics of an in vivo canine vocal fold during phonation. J Acoust Soc Am. 2005 May;117(5):3174-83.
  • Chhetri DK, Head C, Revazova E, Hart S, Bhuta S, Berke GS. Lamina propria replacement therapy with cultured autologous fibroblasts for vocal fold scars. Otolaryngol Head Neck Surg. 2004 Dec;131(6):864-70.

Contact Information

Dinesh K. Chhetri, MD:
dchhetri@mednet.ucla.edu 
(310) 794-4225

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